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Skin Thickness in Different Menopausal Status

KRASEAN PANYAKHAMLERD, M.D.*, NIMIT TAECHAKRAICHANA, M.D.*, SUKANY A CHAIKITTISILPA, M.D.*, PICHAI CHOTNOPPARATPATTARA, M.D.*, ATCHARA KUKULPRASONG, M.D.**, KOBCHITT LIMPAPHA YOM, M.D.*

Affiliation : * Department of Obstetrics and Gynecology, ** Department of Radiology, Faculty of Medicine, Chulalongkorn University, Bangkok I 0330, Thailand.

Abstract
It is well known that skin thickness will decrease in the years after menopause. Women may have climacteric symptoms including those associated with skin alterations as early as during the perimenopausal period. This study was performed to compare the skin thickness of women in their premenopause (N=31), perimenopause (N=35) and early postmenopause (N=46). The mean skin thickness in each group was 2.28 ± 0.39 mm., 2.18 ± 0.35 mm. and 2.02 ± 0.36 mm. respectively. The skin thickness of women in the early postmenopausal group was sig- nificantly lower than those in the premenopausal group, but no difference was found between pre- menopausal and perimenopausal group nor between perimenopausal and early postmenopausal group. Furthermore, we found no correlation between skin thickness and chronological age. In conclusion, the decline in skin thickness of women entering menopause requires a period of time to undergo significant alterations and the study revealed a significant reduction of skin thickness as early as in the course of the early postmenopausal period.

Keywords : Menopause, Skin Thickness


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