A regimen of 200 mg oral mifepristone followed by repeated doses of sublingual misoprostol is safe and effective for second-trimester medical termination up to 20 weeks. Although complete expulsion within 48 hours was lower than previous studies with longer observation periods, complication rates remained low and acceptable. This protocol offers a practical, patient-acceptable alternative in real-world settings.

Preoperative factors, particularly stone diameter and prior surgical history, play a key role in SF outcomes after RIRS. A simple clinical rule based on these variables may support risk stratification and guide patient counseling in routine practice.

Automated nucleic acid extraction reduced false positive rates by 0.78% but increased invalid result rates by 1.18%. It yielded lower DNA yield and purity compared to manual extraction. Despite these limitations, automation remains a practical option for high-throughput processing, offering substantial time and resource savings with manageable invalid result rates.

A dose of 1 mcg/kg of fentanyl administered during the induction phase before intubation results in lower postoperative pain scores at 24 hours compared with 2 mcg/kg in patients with morbid obesity undergoing laparoscopic sleeve gastrectomy. Both fentanyl dosages effectively control intraoperative hemodynamic parameters.

The patients with plaque psoriasis were 10.73 times significantly greater to predict CAVI >8.0 or AS than non-psoriatic group. To prevent cardiovascular events and further long-term complications, early cardiovascular screening with CAVI in psoriasis patients is an optional evaluation tool.

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