Percutaneous Transthoracic Needle Aspiration Biopsy
of Localized Lung Lesions Under Fluoroscopic or Ultra-
sound Guidance
PONGLADA SUBHANNACHART, M.D.*,
THA WETONG KOANANTAKOOL, M.D.***,
ANUCHA TANGTHANGTHAM, M.D.**,
SUTARAT TUNGSAGUNW ATTANA, M.D.*
Affiliation : * Division of Radiology,
** Division of Pathology,
*** Division of Surgery, Central Chest Hospital, Department of Communicable Diseases Control, Nonthaburi 11000.
Thailand.
AbstractDiagnostic percutaneous transthoracic needle aspiration biopsy (TNAB) under tluoro-
scopic or ultrasound guidance was performed in 195 patients with peripheral lung lesions. Final
diagnosis was confirmed in 178 cases. These consisted of 150 cases of malignant and 28 cases of
non-malignant lung lesions. Most cases of the latter belonged to the infectious group. Sensitivity of
TNAB in the diagnosis of malignancy and lung infections were 92.0 per cent and 62.5 per cent
respectively. Needles with different sizes were used and the needle number l8G was found to obtain
both cytological and histological samples and showed the highest sensitivity. Among cases that
TNAB provided both types of samples, histology alone showed higher sensitivity in diagnosis than
cytology alone. However, by cytological examination, malignant tumors could be interpreted for
definite cell type in more cases than by histology. To reach the highest diagnostic yield, the results
of both samples should be combined. We also found that the aspirated samples with solid or
semisolid features were more diagnostic than those with other features. Pneumothorax, the most
common complication of the TNAB procedure, was found in only 2.0 per cent of our
series.
Keywords : Needle Aspiration, Transthoracic, Lung Mass
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