Chronic Eosinophilic Pneumonia : A Case Report

ANAKAPONG PHUNMANEE, M.D.*, WATCHARA BOONS A WA T, M.D., Ph.D.*, DARUNEE JINTAKANON CHAROENSIRI, D.D.S, M.Sc.**, CHUTHATIP LIMKUNACUL,M.D.*

Affiliation : * Division of Pulmonary and Critical Care Medicine, Department of Medicine, ** Department of Pathology, Faculty of Medicine, Srinagarind Hospital, Khon Kaen University, Khon Kaen 40002. Thailand.

AbstractChronic eosinophilic pneumonia (CEP) is a disorder, characterized by a history of pneu- monia (> 2 months) and eosinophilic pulmonary infiltration without any organic causes. We des- cribe a 28-year-old woman who presented with cough, dyspnea and fever for 2 months. She was diagnosed with mild asthma and allergic rhinitis 2 years before being diagnosed with CEP. For a period of 9 months she took no medication. Her chest roentgenogram at this admission revealed patchy infiltration in both upper lung fields. Laboratory data revealed blood eosinophilia (4,284 /mm3), and her serum lgE was mildly elevated (245.8 IU/ml). A computerized tomography of the chest did not show bronchiectasis. CEP was diagnosed from significant eosinophilia in bronchoalveolar larvage fluid and transbronchial biopsy revealed eosinophilic infiltration without any demonstrable infectious agent. The patient was treated with prednisolone 45 mg/day. Her symptoms disappeared and her chest roentgenogram showed nearly complete resolution in 2 and 4 days, consecutively.

Keywords : Eosinophils, Pneumonia

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