Intubating Conditions after Three Different Doses of Rocuroniumt

WANNA SOMBOONVIBOON, M.D.*, PAVENA BUNBURAPHONG, M.D.*, OPAS WHANNA, M.D.*, SURASAK JUAJARUNGJAI, M.D.*, KANCHANA SUKVIV AT. Certificate (Anesthesia Nurse)*

Affiliation : * Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University. Bangkok I 0330. Thailand. t Presented at the 48th Meeting of the Royal College of Anesthesiologists of Thailand, Bangkok. Thailand. 16th August 1998.

AbstractThis randomized controlled trial study evaluated the intubating conditions at I minute after 0.3, 0.6 and 0.9 mg/kg of rocuronium in 108 Thai patients who were enrolled for elective surgery under general anesthesia with fentanyl, thiopental and isoflurane at King Chulalongkorn Memorial Hospital.
Excellent or good conditions were observed in 77.8 per cent (p<0.05) with rocuronium 0.3 mg/kg compared to 94.4 and 97.2 per cent at 0.6 and 0.9 mg/kg of rocuronium, respectively but the excellent condition was 16.7 (p<0.05), 52.8 (p<0.05) and 77.8 per cent (p<0.05) from each dose. In females, the excellent condition was 33.3 (p<0.05), 83.3 and 88.9 per cent while it was only 0, 22.2 and 66.7 per cent (p<0.05) in males. Therefore, rocuronium ~ 0.6 mg/kg should be adequate for intubation. Furthermore, in a situation where an excellent condition is very important, a dose of ~ 0.9 mg/kg of rocuronium is recommended especially in male patients.

Keywords : Rocuronium, Intubation, Muscle Relaxant

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