The He~inki Declaration Regarding Ethics in Clinical Research
HENRY WILDE, M.D.*, YUEN TANNIRANDORN, M.D.**, CHUMSAK PRUKSAPONG, M.D.***
Affiliation : *Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok 10330, **Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok I 0330, *** Department of Surgery, Police Hospital, Bangkok 10330, Thailand.
Powerful forces are again advocating major revisions of the Helsinki Declaration (HD) which was formulated in 1964 to provide guide- lines for ethical conduct of a conference of the World Medical Association. It attempted to inter- pret declarations by the Nurnberg War Crimes Court concerning criminal medical experimentation on prisoners (1946/47) and the United Nations General Assembly's Statement of Universal Human Rights (1948). It has since undergone several reviews (1975, 1983, 1989, 1996) but has served the pro- fession well as a general guideline for ethical clini- cal research. Additional documents dealing with specific topics such as informed consent, induce- ments for study subjects, research in children and prisoners, confidentiality and the obligations of research sponsors and host countries were pub- lished by WHO and the Council for International Organizations of Medical Sciences.
Keywords : Ethics, Helsinki, AIDS
