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Fine Needle Aspiration Cytology of Metastatic Transi- tional Cell Carcinoma to the Livert

NIP A KANJANA VIROJKUL, M.Sc., C.M.I.A.C. *, CHURA IRA T KULARBKAEW, M.D.*, WIBOONCHAI YUTAN A WIBOONCHAI, M.D., Ph.D.*

Affiliation : * Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. t Presented at the Fourth National Cancer Conference, Bangkok, Thailand, November 11-13, 1997.

Abstract
A 63-year-old man presented with a three-month history of painless hematuria. A cysto- scopic examination revealed a diffuse small nodulopapillary growth of the bladder mucosa. Biopsy resulted in the diagnosis of a transitional cell carcinoma (TCC), grade II. Therefore, total cystec- tomy with an ileal conduit was performed and the pathologic examination demonstrated a TCC grade !VIII apparently confined to the mucosa. However, an ultrasonographic study carried out one year later revealed tumor masses in the pelvic cavity and the liver. FNA and needle biopsy of the liver were carried out and the diagnosis of a metastatic TCC was made from the former. Needle biopsy results pointed to a metastatic undifferentiated carcinoma, most likely originating from the TCC. The advantage of FNA is discussed. It is being used with increasing frequency to diag- nose mass lesions in the liver and can identify metastatic tumors which have specific cytologic features that are different from primary liver tumor.

Keywords : Fine Needle Aspiration, Cytology, Transitional Cell Carcinoma, Metastatic, Liver


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