Hyperhomocysteinemia in Patients with Coronary Artery Disease

NITHI MAHANONDA, M.D., F.R.A.C.P., F.A.C.C., F.S.C.A.I.*, WATT ANA LEOWATANA, M.D.**, KIERTUAI BHURIPANYO, M.D.*, MANOON SAMRANTHIN, M.D.*, CHARUWAN KANGKAGATE, M.S. (BIOSTAT)*

Affiliation : * Her Majesty Cardiac Center, ** Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

AbstractHyperhomocysteinemia has been recognized as a risk factor of atherosclerosis. This study was aimed to measure the risk of coronary artery disease in patients with hyperhomo- cysteinemia. Age, HDL level, tHey level and history of DM were independent risk factors for coronary artery disease. The level of tHey of 11.0 mmol/L provides the best sensitivity and spe- cificity of predicting coronary artery disease.

Keywords : Hyperhomocysteinemia, Coronary Artery Disease, Atherosclerosis

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