Erythropoietin Level
Healthy Adultst
NAVAPUN CHARURUKS, M.D.*,
NARIN VORA VUD, M.D.***,
and Hematologic Parameters in
WATCHAREE LIMPANASITHIKUL, Ph.D.**,
KRITTAYA SUTHEESOPHON, M.D.*
Affiliation : * Department of Laboratory Medicine,
** Department of Pharmacology,
*** Department of Medicine, Faculty of Medicine, Chulalongkom University, Bangkok 10330, Thailand.
t Supported by: Rachada-Pisek-Sompoch Grant, Faculty of Medicine, Chulalongkom University, Bangkok 10330.
Thailand and Grant from I anssen Pharmaceutica Ltd., Bangkok I 0310, Thailand.
AbstractSince the major physiological control of erythropoiesis is related to the eryhtropoietin
(EPO) level, correlating the EPO level with hematologic parameters in healthy adults, which
constitutes an inexpensive and simple routine laboratory report, would be very useful. Two hun-
dred healthy adult blood donors, 100 males and 100 females, aged between 17 and 60 years old
were randomly chosen. The EPO reference range was determined by enzyme linked immmuno-
sorbent assay (ELISA) using a reagent kit from Research & Development Systems Inc. The
hematologic values for reticulocyte and red blood cell parameters were assessed using the Tech-
nicon H*3 RTC, an automated blood cell analyzer. The EPO reference range in the studied
population was 2.21-20.95 mU/ml. The correlations between the EPO level and hematologic
parameters were between -0.302 (p
Keywords : Erythropoietin, Reference Range, Correlation Study, Hematologic Parameters, Healthy
Adults
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