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Solitary Keratoacanthoma of the Conjunctiva: Report of a Caset

WASEE TULV AT ANA, M.D.*, PETCH PISARNKORSKUL, M.D.*, PONGSAK WANNAKRAIROT, M.D.**

Affiliation : * Department of Ophthalmology, **Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand. t Presented at the 6th Annual Meeting of the Royal College of Ophthalmologists of Thailand, Bangkok, Thailand, November 26, 1999.

Abstract
Keratoacanthoma characteristically occurs on the skin and is rarely found in the conjunc tiva. We, herein, report a case of a healthy 41-year-old Thai woman presenting with a rapidly grow ing conjunctival mass. The tumor was excised to exclude squamous cell carcinoma. Histopatho logy revealed a cup shaped well-circumscribed proliferation of squamous cells, with a central keratin crater, consistent with a keratoacanthoma. On the literature review, only 12 cases have pre viously been reported in the English language. The mean age of presentation was 40.75 years, with a male preponderance. Presentation of a mass was mostly within 4 weeks after onset. History of foreign material getting into the eye was positive in 5 cases. All cases were successfully treated by excision, except for one case in which malignancy transformation was found, and enucleation was required eventually.
Conjunctival keratoacanthoma is a rare disease. However, this lesion should be well recog nized and not misinterpreted as malignancy. As far as we are aware, this is the first report of con junctival keratoacanthoma from this region.

Keywords : Keratoacanthoma, Conjunctiva, Squamous Cell Carcinoma


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