Peripheral Primitive Neuroectodermal Tumor with Neuronal and Glial Differentiation : Report of a Case Arising in Suprarenal Region

CHAV IT CHANTRANUWAT, M.D.*

Affiliation : * Department of Pathology, Faculty of Medicine, Chulalongkom University, Bangkok 10330, Thailand.

AbstractIt is well known that embryonal neuroectodermal tumors of the central nervous system (CNS) not infrequently display varying amount of neoplastic cells acquiring glial differentiation. In contrast, glial differentiation rarely occurs in primitive neuroectodermal tumors outside the CNS being documented in less than ten cases. The author presents herein a case of peripheral primitive neuroectodermal tumor with prominent glial differentiation identified by the presence of glial fibrillary acidic protein (GFAP) arising in the right suprarenal region of a 32-year-old man, histologically indistinguishable from an ordinary neuroblastoma.

Keywords : Primitive Neuroectodermal Tumor, Neuroglial Differentiation, Suprarenal Region

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