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Penicilliosis-Associated Hemophagocytic Syndrome in a Human Immunodeficiency Virus-Infected Child: The First Case Report in Children

KULKANYA CHOKEPHAIBULKIT, M.D.*, GA VIV ANN VEERAKUL, M.D.*, **, NIRUN VANPRAPAR,M.D.*, ANGKANA CHAIPRASERT, Dr.rer.nat. VORAVARN TANPHAICHITR,M.D.*, SANAY CHEARSKUL,M.D.*

Affiliation : * Department of Pediatrics, ** Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.

Abstract
Infection-associated hemophagocytic syndrome (IAHS) has been found in many systemic infectious conditions with a high mortality rate. Disseminated Penicillium mameffei infection is a common opportunistic condition among HIV-infected patients in many regions in Southeast Asia. We report the first case of IAHS caused by penicilliosis in an HIV-infected child who presented with cytopenias and recovered promptly after antifungal and intravenous immunoglobulin therapy.

Keywords : Penicilliosis, Hemophagocytic Syndrome, HIV-Infected Child


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