The Long Term Outcome Of Thirty Eight Post Transfusion Hepatitis C

SOMPONE PUNY A GUPTA, M.D., M.P.H.*, TAW EERATANA SIWADUNE, B.S., M.S.A.**

Affiliation : *Liver Clinic, Vichaiyut Hospital, Bangkok 10400, **Department of Mathematics, Faculty of Science, Mahidol University, Bangkok 10400, Thailand.

AbstractThirty-eight cases of post-transfustion HCV hepatitis have been followed for 5-24 years. Cirrhosis and hepatocellular carcinoma were found in 44.7 per cent and 13.1 per cent respectively. Cirrhosis was recognised by pathological evidence as early as one and a half years after transfusion and the clinical evidences of decompensated cirrhosis were noted in the fifth year post-transfusion onward. Hepatocellular carcinoma was first recognised in year ten and thereafter. Nine patients died of liver failure or hepatocellular carcinoma during years 8-16 of the follow-up. Therefore, it is of utmost importance to screen out the HCV infected blood donors and to treat the HCV patients as early and as effectively as possible.

Keywords : Post-transfusion Hepatitis C, Cirrhosis, Hepatoma

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