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Growth of Infants with Cow’s Milk Allergy Fed Chicken-Based Formula

Channagan Kangwanpornsiri MD*, Pipop Jirapinyo MD*, Narumon Densupsoontorn MD*, Jiranat Poungkaew MD*, Renu Wongarn BA*, Nuchnoi Thammonsiri BSc*, Channarong Jatutipsompol MSc*

Affiliation : * Division of Nutrition, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand

Background : The recommended formulas for treatments of cow’s milk allergy (CMA) in infants are hydrolyzed protein-based and amino acid-based formulas. However, they are not always affordable. Furthermore, some patients are still allergic to these formulas. Therefore, chicken-based formula has been innovated and used as an alternative formula to treat CMA in these infants.
Objective : To assess the growth of infants with CMA who consumed chicken-based formula compared to normal infants. Material and Method: A prospective study was performed in 34 infants aged 3 to 24 months diagnosed as CMA at Siriraj Hospital. All subjects consumed the chicken-based formula for at least three months. The growth parameters were recorded.
Results : Manifestations occurred in dermatological (78.6%), respiratory (67.9%), and gastrointestinal (53.6%) systems. Mean (±SD) chicken-based formula intake was 77 (±39.6) kcal/kg/d. Weight gains are higher (35.7%), equal (10.8%), and lower (53.5%) than those of normal infants. In addition, length gains were higher (38%), equal (5%), and lower (57%) than those of normal infants. However, the difference of weight and length in chicken-based fed, cow’s milk-allergic infants, and normal infants were not statistically significant (p = 0.141, p = 0.192). None of these infants had severe complications.
Conclusion : Growth parameters of infants fed with chicken-based formula are not different from those of normal infants.

Keywords : Growth, Infant, Milk allergy, Synthetic diet, Thailand


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