Percutaneous Renal Biopsy in Children
ACHRA SUMBOONNANONDA, M.D.*, KRISSADA SRAJAI, M.D.*,
ARUN VONGJIRAD, M.D.*, VIBUL SUNTORNPOCH, M.D.*,
PAISAL PARICHATIKANOND, M.D.**
Affiliation : *Department of Pediatrics,
**Department of Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
AbstractThe authors studied the percutaneous renal biopsies performed in the Department of
Pediatrics, Siriraj Hospital from January 2000 to March 2001 in order to evaluate the safety and
benefit of the procedure. Eighty-five patients (90 episodes) were included in the study, aged 7.8±
3.7 year (range 16 months to 16 years), with a male to female ratio of 1.2:1. Nephrotic syndrome
(42.3%) and systemic lupus erythematosus (23.5%) were the two most common indications for
biopsy. The kidney was localized by ultrasound prior to the procedure in nearly all cases (97.7%).
Premedication with Ketamine was adequate in most patients (91.1%). A modified 13 G Vim
Silverman needle was used to obtain 1-4 biopsy cores. The mean number of glomeruli obtained was
44.0±29.9, with failure to obtain renal tissue in 6 episodes (6.6%). Percutaneous biopsy was per
formed twice in one patient without success and the patient eventually underwent an open biopsy.
The most common complication was hematuria (74.4%), of these, gross hematuria was found in
23.3 per cent. Blood transfusion was needed in 2 patients, one of them also needed embolization
to control bleeding. Transient hypotension occurred in 1 patient. Transient hypertension occurred in
6 episodes (6.6%). Muscle twitching occurred in 2 episodes and was treated with diazepam intra
venously. Hypertension and muscle twitching only occurred in those who received ketamine. The
Clinical Benefit Score was 2 (information yielding a definite diagnosis and/or prognosis, alterna
tively allowing a change in, or support of, therapy) in 89.4 per cent.
It was concluded that the present practice of renal biopsy is safe, with high clinical benefit
score. It remains to be studied whether an ultrasound guidance biopsy with a newer biopsy device
will lower the incidence of complications even further.
Keywords : Renal Biopsy, Clinical Benefit, Complication
All Articles
Download
