Prevalence of Thyroid Antibodies in Thai Patients with
Chronic Idiopathic Urticariat
PRISANA KULLAV ANUAY A, M.D.*, SIRIPEN PUAVILAI, M.D.*,
GOBCHAI PUAV ILAI, M.D.*, SUWANNEE CHANPRASERTYOTHIN, M.Sc.*
Affiliation : * Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
t Presented at the Annual Meeting of the Dermatological Society of Thailand, March 2-3, 2000.
AbstractOne hundred Thai patients with chronic idiopathic urticaria (CIU) were studied to determine
the prevalence of thyroid antibodies in comparison to 100 age- and sex-matched healthy volunteers.
It was found that 21 patients (21%) with CIU were positive for thyroid antibodies. Among normal
volunteers, only nine cases (9%) had elevated titers of thyroid antibodies. The frequency of thyroid
antibodies in the chronic urticaria group was significantly more common than the control group
(chi-square= 4.75, p=0.03). Among 21 patients with CIU who were positive for thyroid antibodies,
9 cases were negative for thyroid antibodies when repeating the tests after 3 months. Only 12
patients still had persistent elevation of antibodies after 3 months and thyroid function test was per
formed in these 12 patients. It was found that 9 cases had autoimmune thyroiditis with euthyroidism.
One case had subclinical hyperthyroidism. One case had autoimmune hyperthyroidism. One case had
subclinical hypothyroidism.
Keywords : Hives, Autoimmune Thyroiditis, Hypothyroidism, Hyperthyroidism
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