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AIDS-Related Primary Central Nervous System Lymphoma: Prolonged Remission Associated with Highly Active Antiretroviral Therapy

VERAJIT CHOTMONGKOL, M.D.*, MONTIEN PESEE, M.D.**

Affiliation : * Department of Medicine, **Division of Radiotherapy, Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

Abstract
A 36-year-old HIV -seropositive man developed progressive confusion and unilateral tremor of the hand. His medical history included cryptococcal meningitis and CMV colitis. CT scan revealed a single hyperdense mass with minimal peripheral enhancement at the region of the cerebral peduncle and pons, causing obstructive hydrocephalus. He was treated with ventriculo-peritoneal shunt and cranial radiotherapy. He also received treatment with highly active antiretroviral therapy (HAART). A CD4+ cell count was increased from 2 to 345 cells/mm3 He returned to normal function for *about 32 months after treatment.

Keywords : AIDS, Primary Central Nervous System Lymphoma, HAART


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