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The Role of Carbamylated Hemoglobin in Identifying Acute and Chronic Renal Failure

ADIS TASANARONG, M.D.*, TADA SEUBLINVONG, M.D.**, SOMCHAI EIAM-ONG, M.D.***

Affiliation : * Nephrology Unit, Department of Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, ** Department of Biochemistry, *** Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkom University, Bangkok 10330, Thailand.

Abstract
Carbamylated hemoglobin (CarbHb) levels expressed as valine hydantoin (VH) were measured by high performance liquid chromatography (HPLC) in patients with acute renal failure (ARF, n=35) and chronic renal failure (CRF, n=39). CarbHb levels in CRF patients were approxi mately 2.5 times of those in ARF ones (121.2 ± 8 vs 54.8 ± 6 jlgVH/gHb, p

Keywords : Carbamylated Hemoglobin, Valine Hydantoin, Acute Renal Failure, Chronic Renal Failure


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