Nuchal Translucency in Normal Fetuses in a Thai
Population
PANYU PANBURANA, M.D.*, SAUWAKON AJJIMAKORN, M.D.*,
ADITHEP JAOVISIDH, M.D.*, PONGLADDA TUNGKAJIWANGOON, B.Sc*
Affiliation : * Down Syndrome Screening Clinic, Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi
Hospital, Mahidol University, Bangkok 10400, Thailand.
AbstractThe purpose was to study nuchal translucency thickness of normal Thai fetuses in the first
trimester. From January 1996 to June 1999, there were I ,970 pregnant women, whose gestational
ages were between 10 to 13+6 weeks of gestation, who attended the Down syndrome screening
clinic. Nuchal translucency (NT) thickness measurement was used as the screening method for
Down syndrome. When the result showed an increased risk for Down syndrome, the patient was
counselled and the invasive test for the definite diagnosis was optional. Pregnant women who had
had an abortion and/or congenital anomaly babies were excluded. Only pregnant women who had
normal newborns were recruited in this study. There were I ,631 pregnant women who had normal
newborns in this study. The mean maternal age was 28.70±5.14 years. There were 222 (13.6'7r)
pregnant women whose ages were more than or equal to 35 years. There was quadratic correlation
of an increase in nuchal translucency and the crown-rump length (CRL) in normal fetuses in the
first trimester. The quadratic equation was log NT= 1215 x JO-l CRL-8.7 x JO-l CRU -3.7037.
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The normal fetuses with nuchal translucency thickness more than or equal to 2.5 mm were found
in 1.23 per cent in this study. In conclusion, there was quadratic correlation of nuchal translucency
thickness and crown-rump length of first trimester fetuses in a Thai population.
Keywords : Nuchal Translucency, The First Trimester, Thai Population
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