Risk Factors for Pseudomonas aeruginosa Bacteremia in
Thai Patientst
KRITTECHO SIRIPASSORN, M,D.*, SOMPORN SANTIPRASITKUL, M.Sc. **,
SUTHIPOL UDOMPANTHURAK, M.Sc.***, VISANU THAMLIKITKUL, M.D.****
Affiliation : * Bamrasnaradura Hospital, Department of Communicable Disease Control, Nonthaburi 11000,
**Center for Nosocomial Infection Control,
***Department of Research Promotion,
****Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
t This study was presented at the 171h Annual Meeting of the Royal College of Physicians of Thailand in April 2001
and received an award.
AbstractA case control study to determine the risk factors for P. aeruginosa bacteremia was con
ducted in patients admitted to Siriraj Hospital in 1998.
The case group consisted of 65 patients with P. aeruginosa bacteremia. There were 3 con
trol groups. 65 patients with E. coli bacteremia, 64 patients with S. aureus bacteremia and 65 patients
without bacteremia. Demographic information and potential risk factors i.e. type of infection, asso
ciated diseases/conditions, procedures/surgery, previous/current use of antibiotics and previous/current
use of immunosuppressive/cytotoxic agents were extracted from the patients' medical records and
compared. Univariate analysis revealed that the factors associated with P. aeruginosa bacteremia
were infections acquired while hospitalized, hematologic malignancy, neutropenia, COPD, antibiotic
receivers, cytotoxic agents receivers. However, multivariate analysis revealed that only hematologic
malignancy, infections acquired while hospitalized and previous use of parenteral antibiotics were risk
factors for P. aeruginosa bacteremia.
Keywords : Pseudomonas aeruginosa Bacteremia, Risk Factor
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