Severe Upper Gastrointestinal Hemorrhage in the Newbornt

LUMDUAN WONGSAWASDI, M.D.*, NUTHAPONG UKARAPOL, M.D.*, SOMPORN CHOTINARUEMOL, M.D.*

Affiliation : * Department of Pediatrics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand. t Presented at the 14th Annual Meeting of the Gastroenterological Association of Thailand, Kanchanaburi, 13-15 December 2000.

AbstractThree infants with severe upper gastrointestinal hemorrhage with esophagogastroduodeno scopic (EGD) findings were reported. The underlying conditions of these infants included Down's syndrome, hypoplastic left heart, arid diaphragmatic hernia. The precipitating factors were identified in all cases, including prenatal stress, hypoxemia, prolonged ventilatory support, and gastroesopha geal reflux. The EGD findings were composed of multiple gastric ulcers and a duodenal ulcer in the first 2 cases, whereas esophagitis and gastritis were noted in the last case. These ulcers were classified as secondary peptic ulcers. All cases responded well to medical treatment, including ranitidine, sucralfate, omeprazole, cisapridt;.._. and octreotide.

Keywords : Gastrointestinal Hemorrhage, Newborn, Esophagogastroduodenoscopy

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