A Clinical Study of Crystal-Proven Gouty Arthritis in a
University Hospital t
WORAW IT LOUTHRENOO, MD*, NUNTANA KASITANON, MD*,
WARAPORN SUKITA WUT, BSc*, RAMJAI WICHAINUN, BSc*
Affiliation : * Division of Rheumatology, Department of Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200,
Thailand.
t Present in part at the 10'" Asia Pacific League of Association for Rheumatology Meeting, 1-6 December 2002, Bangkok,
Thailand.
AbstractThe clinical features of 567 patients with crystal proven gout (489 males, 78 females) seen in
a University Hospital in northern Thailand was reviewed. The mean age at onset and mean duration
of disease was 60.0 ± 11.7 years and 5.2 ± 4.8 years, respectively. Recurrent attacks accounted for 94
per cent. The knee and ankle were the 2 most common joints affected during the first attack and each
one was seen in 55.6 per cent of cases. During a recurrent attack, the ankle, knee and first metatar
sophalangeal joint were the 3 most common joints affected and were seen in 94.5 per cent, 81.2 per
cent and 80.2 per cent of cases, respectively. Thirty-six per cent of the patients had tophi. Hypertension,
hyperlipidemia, diabetes mellitus and ischemic heart disease were commonly associated diseases.
Thirty-five per cent had renal calculi, and fifty-four per cent had renal insufficiency. Of 59 patients who
tested with normal renal function, twelve per cent were hyperexcretor. The clinical features of gout seen
in the university hospital in northern Thailand were similar to those reported in Bangkok, but with a
higher incidence of tophaceous gout, renal failure and renal calculi.
Keywords : Gout, Hyperuricemia, Uric Acid, Treatment, Outcome, Monosodium Urate, Crystal
Induced Arthritis
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