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Correlation between Random Urinary Protein-to-Crea tinine Ratio and Quantitation of 24-hour Proteinuria in Preeclampsia

WARALAK YAMASMIT, MD*, KITTI WONGKITISOPHON, MD*, DHIRAPHONGS CHAROENVIDHY A, MD*, BOONCHAI UERPAIROJKIT, MD*, SURASITH CHAITHONGWONGW ATTHANA, MD**

Affiliation : * Division of Maternal-Fetal-Medicine. Department of Obstetrics and Gynecology, **Clinical Epidemiology Unit. Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.

Abstract

Objective : To determine whether random urinary protein-to-creatinine ratio correlated with the quantitation of 24-hour proteinuria in cases of preeclampsia.
Design : Cross-sectional descriptive study.
Subjects : Pregnant patients hospitalized in the obstetric ward, King Chulalongkorn Memorial Hospital due to preeclampsia.
Method : The random urine specimens were obtained from the eligible subjects for protein to-creatinine ratio determination, the subjects were then instructed to collect 24-hour urine samples for protein measurement.
Results : Twenty-five pregnant patients completed the study. There was a strong correlation = between the random urinary protein-to-creatinine ratio and the quantitation of 24-hour proteinuria (r 0.929, p < 0.001).
Conclusion : The presented data support a strong correlation between random urinary pro tein-to-creatinine ratio and quantitation of 24-hour proteinuria in hospitalized pregnant patients with preeclampsia.

Keywords : Urinary Protein-to-Creatinine Ratio, 24-Hour Proteinuria, Preeclampsia


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