Detection of Coronary Stenoses in Chronic Stable Angina by Multi-Detector CT Coronary Angiography
Melissa Panmethis MD*, Somjai Wangsuphachart MD*, Pairoj Rerkpattanapipat MD*, Suphot Srimahachota MD***, Wacin Buddhari MD**, Weeranuch Kitsukjit MSc*
Affiliation : * Department of Radiology, Faculty of Medicine, Chulalongkorn University ** Cardiology Unit, Department of Medicine, Faculty of Medicine, Chulalongkorn University *** Cardiac Center, King Chulalongkorn Memorial Hospital, Thai Red Cross Society
Objective : To assess the accuracy for detection of coronary stenoses in chronic stable angina patients.
Materials and Methods : Twenty-four chronic stable angina patients, referred for conventional coronary an-
giography by the indication of positive stress tests or clinical highly suspicion of coronary artery disease were
enrolled. MDCT coronary angiography (MDCTCA) and conventional coronary angiography (144 coronary
vessels) were performed within one month. Accuracy of MDCTCA for predicting significant coronary artery
stenoses was analyzed.
Results : Five patients were excluded due to the total Agaston calcium score more than 500. Therefore, 114
vessels or 209 segments from 19 patients (9 males and 10 females) were available for analysis, and 186
segments were assessable (89%). Of all assessable segments, 13 from 20 significant lesions (65%) and 158
from 167 normal or non-significant lesions (95%) were correctly detected by MDCTCA. The sensitivity,
specificity, positive and negative predictive values to detect significant coronary artery stenoses in terms of
vessel are 82%, 96%, 79%, and 97% respectively.
Conclusion : Coronary CT angiography provides accurate assessment of coronary luminal artery narrowing
and shows the ability to exclude significant coronary artery stenoses in patients with chronic stable angina.
Keywords : Coronary CTA, Chronic stable angina, Coronary stenosis, Accuracy
