Bullous Systemic Lupus Erythematosus
Induced by UVB: Report a Case
Proadpran Nasongkhla MD*,
Walaiorn Pratchyapruit MD*, Hachiro Tagami MD, PhD**
Affiliation :
* Institute of Dermatology, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand
** Emeritus Professor of Dermatology, Tohoku University School of Medicine, Sendai, Japan
Bullous systemic lupus erythematosus (BSLE) is a rare blistering disease that dramatically responds to dapsone
administration without leaving any scar. Generally, those patients with BSLE meet the criteria for systemic lupus
erythematosus, but some have a widespread vesiculobullous eruption only as an initial manifestation without any specifi c
clinical or laboratory fi ndings that fulfi ll the American College of Rheumatology diagnostic criteria for SLE. The authors
report here a middle-aged female patient, whose diagnosis of BSLE was suspected at fi rst from the characteristic
vesiculobullous eruption, histopathology, immunofl uorescent pattern, and positive antinuclear antibody, who was later
confi rmed to have UVB photosensitivity that induced the typical skin lesions.
Keywords : Bullous systemic lupus erythematosus, Phototest, UVB, Dapsone
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