Adverse Pregnancy Outcomes in Gestational Diabetes Mellitus
Dittakarn Boriboonhirunsarn MD, MPH, PhD*, Pattarawalai Talungjit MD*, Prasert Sunsaneevithayakul MD*, Ratre Sirisomboon BSc*
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University
Objective : To evaluate adverse pregnancy outcome in women diagnosed with gestational diabetes mellitus
(GDM) at Siriraj hospital.
Study
Design : Cross- sectional study.
Setting : Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University.
Materials and Methods : One hundred and sixty two women who were diagnosed with GDM and who received
treatment following clinical practice guideline at Siriraj hospital were enrolled. Data were abstracted from
medical record regarding adverse pregnancy outcomes of both the mothers and their infants.
Results : The most common clinical risk for GDM was age > 30 years (116 cases, 71.6%), followed by family
history of diabetes mellitus (81 cases, 50%) and obesity (47 cases, 29%). Majority of the women were GDM
class A1 (156 cases, 96.3%) and only six cases (3.7%) were GDM class A2. Maternal complications were
found in 35 cases (21.6%) and the most common complications were postpartum hemorrhage (17 cases,
10.5%), mild preeclampsia (6 cases, 3.7%) and severe preeclampsia (3 cases, 1.9%). The most common
neonatal complication was hypoglycemia (111 cases, 68.5%). This occurred in all infant of GDM class A2
mothers. Macrosomia was found in 29 cases (17.9%). No significant differences in maternal and neonatal
complications were found between GDM class A1 and class A2.
Conclusion : Women with GDM who were diagnosed and treated following treatment guidelines demonstrated
no severe maternal and neonatal complications.
Keywords : Pregnancy outcomes, Gestational diabetes mellitus
