Risk Factors of First Peritonitis Episode in Thai CAPD Patients
Dhavee Sirivongs MD*, Cholatip Pongskul MD*, Thathsalang Keobounma MD*, Darunee Chunlertrith MSc**, Kanokkorn Sritaso MSc**, Jeff Johns PhD***
Affiliation : * Division of Nephrology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen ** Kidney and Artificial Kidney Unit, Srinagarind Hospital, Khon Kaen University, Khon Kaen *** Faculty of Pharmaceutical Science, Khon Kaen University, Khon Kaen
Background : Peritonitis is a major complication of continuous ambulatory peritoneal dialysis (CAPD) pa-
tients. Information on the specific risk of peritonitis is important in reducing this common complication.
Materials and Methods : A single center, retrospective cohort study was done to assess time to first peritonitis
event and risk factors in Thai CAPD population.
Results : Between January 1995 and December 2005, 322 incident CAPD patients were recruited for the
present study. During the study period of 4,281 patient-months, 198 episodes of first peritonitis were recorded.
The median peritonitis-free time was 13.7 months. A Cox regression model showed that an increase in level of
baseline albumin and hematocrit by 1 g/dL and 1% would decrease risk of peritonitis by 27% and 3%,
respectively (hazard ratio (95%CI): 0.73 (0.59-0.91) and 0.97 (0.94-1.00)). A neutral effect of self and caregiver
performer was observed in the present study.
Conclusion : The present study confirmed the susceptibility of hypoalbuminemia and anemia to peritonitis.
Awareness of particular risk groups should be achieved to prevent peritonitis.
Keywords : Continuous ambulatory peritoneal dialysis, First peritonitis episode, Risk factors
