Thailand Diabetes Registry Project: Type of Diabetes, Glycemic Control and Prevalence of Microvascular Complications in Children and Adolescents with Diabetes
Supawadee Likitmaskul MD*, Suttipong Wacharasindhu MD**, Petch Rawdaree MD***, Chardpraorn Ngarmukos MD****, Chaicharn Deerochanawong MD*****, Sompongse Suwanwalaikorn MD**, Thanya Chetthakul MD******, Pongamorn Bunnag MD****, Natapong Kosachunhanun MD*******, Nattachet Plengvidhaya MD********, Rattana Leelawatana MD*********, Sirinate Krittiyawong MD**********, Yupin Benjasuratwong MD***********, Thongchai Pratipanawatr MD************
Affiliation : * Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University ** Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, *** BMA Medical College and Vajira Hospital **** Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University ***** Rajavithi Hospital, ****** Department of Medicine, Maharat Nakhon Ratchasima, Hospital ******* Department of Medicine, Faculty of Medicine, Chiang Mai University ******** Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University ********* Department of Medicine, Faculty of Medicine, Prince of Songkla University ********** Theptarin General Hospital, *********** Department of Internal Medicine, Phramongkutklao Hospital ************ Deptpartment of Medicine, Faculty of Medicine, Khon Kaen University
Objective : To determine the etiology, glycemic control and prevalence of microvascular complications in Thai
diabetic patients who were diagnosed at the age of less than 18 years and who attended diabetes clinics in
university or tertiary care hospitals.
Materials and Methods : A cross-sectional, multi-center, hospital-based diabetes registry was carried out from
diabetes clinics of 11 tertiary centers. Demographic data including laboratory results and microvascular
complications were recorded.
Results : Two-hundred-and-fifty out of the 9419 (2.66%) diabetic patients were diagnosed before the age of 18
years, 78% had Type1 diabetes (T1DM), 18.4% had Type2 diabetes (T2DM) and 3.6% had other types of
diabetes. Mean HbA1C of T1DM was 9.3 ± 2.5, T2DM was 9.7 ± 2.6 and other types of diabetes were 8.6 ± 4%.
The majority of patients had poor glycemic control according to ADA and WHO guidelines. The percentage of
patients who had diabetes for more than 5 years but had not been screened for nephropathy and retinopathy
were 57.7% and 16% in T1DM and were 46.4% and 14.2% in T2DM respectively. A significant correlation
between microvacular complications (nephropathy and retinopathy) and duration of disease was found in
T1DM (p <0.001).
Conclusion : The majority of Thai children and adolescents with diabetes had T1DM and unsatisfactory
glycemic control. Screening for microvascular complications was under international standard. The national
strategic plan for management of this disease especially in this age group should be urgently implemented.
Keywords : Juvenile diabetes, Children and adolescents with diabetes, Type of diabetes, Glycemic control, Microvascular complications
