Osteoporosis in Different Age-Groups and Various Body
Mass Index (BMI) Ranges in Women Undergoing
Bone Mass Measurement at King Chulalongkorn
Memorial Hospital
Kunthida Rithirangsriroj MD*,
Krasean Panyakhamlerd MD*, Sukanya Chaikittisilpa MD*,
Tawatchai Chaiwatanarat MD**, Nimit Taechakraichana MD*
Affiliation :
* Department of Obstetrics and Gynecology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand
** Division of Nuclear Medicine, Department of Radiology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand
Objective : To determine percentage of osteoporosis at femoral neck and lumbar spine (L1-L4) in women with different age
group and various BMI ranges.
Material and Method: The present study was conducted in 4,528 women of > 40 years who underwent first BMD measurement
at King Chulalongkorn Memorial Hospital between 2000 and 2010. Bone mineral density (BMD) of femoral neck (non-
dominant side) and lumbar spine (L1-L4) was measure by Dual-energy x-ray Absorptiometer (DXA). The percentage of
osteoporosis was determined by WHO cutoff value using Thai nationwide reference database.
Results : The percentages of osteoporosis at femoral neck (FN) in age group of 40 to 49, 50 to 59, 60 to 69, and > 70 years
were 6.2%, 7.4%, 24.4%, and 51.8% respectively. The corresponding figures for lumbar spine (LS) were 3.4%, 5.6%,
12.7%, and 20.9% respectively. The percentage of osteoporosis seems to increase strikingly after 60 years at both sites. The
percentage of osteoporosis at FN in underweight, normal weight, overweight and obesity were 52.1%, 20.3%, 15.7%, and
9.4% respectively. The corresponding figures for LS were 22.8%, 12%, 4.8%, and 5.9% respectively. Over 30% of women
of age > 60 years with BMI of less than 23 kg/m2 had osteoporosis by the studied criteria.
Conclusion : The percentage of osteoporosis seemed to be increasing with age and declining with BMI. Using the WHO cutoff
value and Thai reference database, the percentage of femoral neck osteoporosis appeared to be higher than the lumbar spine.
In the present study, the authors found that women of > 60 years with BMI of less than 23 kg/m2 posed a substantial percentage
of osteoporosis.
Keywords : Osteoporosis, Bone mineral density (BMD), Body mass index (BMI)
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