Paraurethral Leiomyoma: A Case Report
Patou Tantbirojn MD*, Lalana Sansopha MD*, Voranuch Thanakit MD*, Nakarin Sirisubya MD**
Affiliation : * Department of Pathology, Faculty of Medicine, Chulalongkorn University ** Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University
A paraurethral leiomyoma is a rare benign hormone-dependent tumor of mesenchymal origin. A 43-year-old woman presented with a palpable mass near the urethral opening with no abnormal urinary symptom. Simple excision was performed. Histopathological diagnosis was paraurethral leiomyoma with confirmation by immunohistochemical study. Further hormonal study of the tumor yielded positive estrogen and progesterone receptor expression, suggesting conservative treatment with gonadotropin-releasing hormone (GnRH) agonist or antagonist may have a role as an alternative treatment in an inoperable case.
Keywords : Paraurethral leiomyoma, Estrogen receptor, Progesterone receptor
