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Metabolic Syndrome among Obese Indonesian Chinese Adolescent (The Petai Cchina Study)

Roy Panusunan Sibarani, Achmad Rudijanto, Jacqueline Dekker, Robert J Heine

Affiliation : Pantai Indah Kapuk Hospital, Jakarta, DKI Jakarta, Indonesia

Background and Aims. Childhood obesity is one of the most serious and urgent public health problems in both developed and developing countries(1). Puberty itself is a state of relative insulin resistance and there is an increase in basal and stimulated insulin secretion during the progression through normal puberty(2), and metabolic syndrome occurs with a high rate in overweight youth. This Petai China Study determines the prevalence of metabolic syndrome among the obese adolescents in Indonesia for estimating the magnitude of this health problem and evaluate a definition for its early diagnosis in the young population.
Materials and Methods. Subjects were taken by a cluster random sampling from the list of junior high school and high school located in north Jakarta. A cross-sectional study with a survey method was done to students from 5 schools agreed for the study. Physical examination and anthropometric measurement were done to all participating students. A fasting blood venous sample was collected among the overweight population to determine glucose, trygliceride, HDL cholesterol and insulin levels, and also among lean students for study control. Prevalence of the metabolic syndrome was estimated according to the National Cholesterol Educa- tion Program Adult Treatment Panel III- Asia Pacific Perspective(3).
Results. Data were analyzed out of 510 adolescents participants, 51% were female, with the average of 14.84 +/- 1.46 year of age. Mean of BMI is 22.32 +/- 4.77 kg/m2. The prevalence rate of obesity was 4.9% (95% CI 26.31 - 36.75). With the blood test done to 47 overweight students and 11 lean students referring to the parents permission. Metabolic syndrome found in 29.78% of population. Out of 14 obese subjects (BMI exceeding the 95th percentile) metabolic syndrome criterions found in 5 students (35.71%). The prevalence rate of the metabolic syndrome increased significantly with increasing insulin resistance ( P for trend, < 0.001 ) after adjustment for sex group and degree of obesity.
Conclusion. The prevalence of the metabolic syndrome is high among overweight Chinese adolescents in Jakarta, Indonesia and it increases with worsening obesity.

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