Estimated Volumetric Bone Mineral Density in a Rural Thai Men and Women: Khon Kaen Osteoporosis Study (KKOS)
Chatlert Pongchaiyakul, MD*, Tuan V Nguyen, MD**, Chingching Foocharoen, MD***, Rajata Rajatanavin, MD****
Affiliation : * Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine, Khon Kaen University ** Garvan Institute of Medical Research, University of New South Wales, Sydney, Australia *** Division of Rheumatology and Immunology, Department of Medicine, Faculty of Medicine, Khon Kaen University **** Division of Endocrinology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University
The authors examined the areal bone mineral density (aFNBMD) and estimated volumetric bone mineral density at the femoral neck (vFNBMD) in rural Thai men and women. A total of 181 men and 255 women, between 20 and 84 years of age, living in rural areas of Khon Kaen province, were randomly selected. Areal FNBMD and estimated v FNBMD were determined using dual energy X-ray absorptiometry (DPX-IQ, GE Lunar Corp, Madison, WI). Men had a significantly higher aFNBMD than women, whereas the estimated vFNBMD was similar regardless of sex. The peak for the aFNBMD vs. vFNBMD was observed between 20 and 29 vs. 30 and 39 years of age in men and women, respectively. The prevalence of osteoporosis in men and women using estimated vFNBMD vs. aFNBMD cut-offs was 19 and 14.2 vs 11.8 and 26 percent, respectively. Prevalence increased with age. Estimated vFNBMD shows only small sex-correlated differences in bone density. Estimated vFNBMD was more sensitive than aFNBMD, when used to define the osteoporotic cut-offs in men, while it was less sensitive than aFNBMD in women.
Keywords : Osteoporosis, Bone mineral density, Asians, Epidemiology
