The Prevalence and Risk Factors of Osteoporosis in Thai Renal-Transplant Patients
North Techawathanawanna MD*, Yingyos Avihingsanon MD*, Kerkiat Praditpornsilpa MD*, Kannaungnit Kingpetch MD**, Sompong Suwanwalaikorn MD*, Talerngsak Kanjanabuch MD*, Somchai Eiam-Ong MD*, Kriang Tungsanga MD*
Affiliation : * Department of Medicine, Faculty of Medicine, Chulalongkorn University ** Department of Radiology, Faculty of Medicine, Chulalongkorn University
Objectives : To determine the prevalence and risk factors of osteoporosis after renal transplantation in Thai
patients.
Materials and Methods : A single-center cross-sectional study of bone mineral density was conducted in 102
Thai renal allograft recipients. Correlations were made between the clinical parameters and the occurrences
of osteoporosis.
Results : The prevalence of osteoporosis was 24.5%, 9.8% and 26.4% at lumbar vertebrae, hip region, and any
sites, respectively. Binary logistic regression analysis revealed that cumulative dosage of steroids was signifi-
cantly correlated with osteoporosis of the lumbar spine (p = 0.023, adjusted OR = 1.005), while body mass
index (p = 0.005, adjusted OR = 0.738) and age (p = 0.052, adjusted OR = 1.077) were correlated with
osteoporosis of the hip region.
Conclusion : Osteoporosis is common in Thai renal allograft recipients, particularly of the lumbar vertebrae.
Cumulative dosage of steroids is the most important risk factor of low BMD of the lumbar vertebrae.
Keywords : Osteoporosis, Renal Transplantation, Dual Energy X-ray Absorptiometry
