Histopathologic Consistency between Endometrial Hyperplasia Diagnosis from Endometrial Curettage and Pathologic Diagnoses from Hysterectomy Specimens
Somneuk Jesadapatrakul, MD* Siriwan Tangjitgamol, MD**, Sumonmal Manusirivitaya,MD**
Affiliation : * Department of Pathology, Bangkok Metropolitan Administration Medical College and Vajira Hospital ** Department of Obstetrics and Gynecology, Bangkok Metropolitan Administration Medical College and Vajira Hospital
Objectives : To evaluate the consistency between histopathology of endometrial hyperplasia (EMH) from
endometrial curettage and those from the subsequent hysterectomy specimen. The co-incidental finding of
endometrial carcinoma in patients with EMH was also studied.
Materials and Methods : All patients who had a diagnosis of EMH from the curettage procedure and underwent
hysterectomy, between January 1995 and December 2004, were identified. The histopathology of the curet-
tage specimens were compared to those of the hysterectomy specimens.
Results : The histopathologic subtypes of EMH from the curettage specimens of 46 patients included in the
study were: simple or complex hyperplasia in 30 cases and atypical simple or complex hyperplasia in 16 cases.
The consistency rate of endometrial tissue from curettage and hysterectomy specimens was 41.3%. The consis-
tency rates were 62.5% and 30.0% in patients with atypical EMH and EMH without atypia respectively. Eight
cases (17.4%) of EMH also had co-incident endometrial carcinoma.
Conclusion : The consistency rate of endometrial tissue from curettage and hysterectomy specimens was only
modest. This rate was lower in EMH without atypia.
Keywords : Endometrial hyperplasia, Fractional curettage, Hysterectomy, Consistency
