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Rapidly developed Secondary Cutaneous Squamous cell Carcinoma after Post-Surgical Radiation Therapy for Breast Cancer

Kengkart Winaikosol MD*, Palakorn Surakunprapha MD*

Affiliation : * Plastic & Reconstructive Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

Background : Radiation therapy is generally accepted treatment of choices for many benign and malignant tumors. A potential late sequela is the development of secondary malignancies around the treated zone.
Objective : To report a case of rapid development of a secondary cutaneous squamous cell carcinoma, as a potential adverse sequence of post-radiation therapy. Material and Method: A case report and a literature review are provided.
Results : A middle aged woman with locally advanced breast cancer of her left breast developed a secondary squamous cell carcinoma at two years after radiotherapy.
Conclusion : A post-radiation cutaneous carcinomas is an uncommon complication of radiation therapy. Diagnosis of the secondary malignancy is often delayed because of its similarities with post-radiation skin lesion or the recurrence of the original tumors.

Keywords : Secondary malignancy, Post-operative radiation, Squamous cell carcinoma, Breast cancer


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MEDICAL ASSOCIATION OF THAILAND
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