Kengkart Winaikosol MD*, Palakorn Surakunprapha MD*
Affiliation : * Plastic & Reconstructive Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Background : Radiation therapy is generally accepted treatment of choices for many benign and malignant tumors. A potential
late sequela is the development of secondary malignancies around the treated zone.
Objective : To report a case of rapid development of a secondary cutaneous squamous cell carcinoma, as a potential adverse
sequence of post-radiation therapy.
Material and Method: A case report and a literature review are provided.
Results : A middle aged woman with locally advanced breast cancer of her left breast developed a secondary squamous cell
carcinoma at two years after radiotherapy.
Conclusion : A post-radiation cutaneous carcinomas is an uncommon complication of radiation therapy. Diagnosis of the
secondary malignancy is often delayed because of its similarities with post-radiation skin lesion or the recurrence of the
original tumors.
Keywords : Secondary malignancy, Post-operative radiation, Squamous cell carcinoma, Breast cancer
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