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Benign Lymphoepithelial Cyst of Parotid Glands in HIV-Positive Patient

Natthaporn Piyasatukit MD*, Surajit Awsakulsutthi MD*, Jutatip Kintarak MD**

Affiliation : * Department of Surgery, Faculty of Medicine, Thammasat University, Pathumthani, Thailand ** Department of Pathology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand

Parotid enlargement mostly results from benign lymphoepithelial cysts (BLCs) in HIV-positive patients, as this can often be the first indication of human immunodeficiency virus infection. BLCs develop secondary to a benign lymphoproliferative disease that is not a tumor but HIV-related reaction, yet pathophysiology was still unclear. FNA cytology is considered the basic and minimal invasive diagnostic tool. BLCs can expand and distort the patient’s facial appearance. This is a cosmetically deforming disease entity as well as the many treatments that accompany it. Choices of treatment are anti-retroviral therapy, repeated fine-needle aspiration and drainage, radiotherapy, sclerotherapy and surgery. The patient presented in this paper is a surgical case control for our findings upon review of the literature. Based on this case control and our review of the literature, it is concluded that surgical intervention offers the best complete response to the disease and cosmetic result for these patients.

Keywords : Benign lymphoepithelial cyst, Parotid mass, HIV


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