Incidental Finding of Metastatic Cutaneous Malignant Melanoma at Uterine Leiomyoma, A Thai University Hospital Experience: A Case Report
Athita Chanthasenanont MD*, Tongta Nantakomon MD*, Jutatip Kintarak MD**, Nophadol Vithisuvanakul MD***, Densak Pongrojpaw MD*, Komsun Suwannarurk MD*
Affiliation : * Department of Obstetrics and Gynecology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand ** Department of Pathology and Forensic Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand *** Department of Radiology, Faculty of Medicine, Thammasat University, Pathumthani, Thailand
Background : Metastatic malignant melanomas to the uterus are extremely rare; to our knowledge, no more than 13 cases
have been reported to date.
Case Report : A 44-years-old multigravida woman presented with a black and irregular surface mass at medial aspect of left
thigh. There was also an enlarged left groin node. Wide excision with lymph node dissection revealed malignant melanoma.
Further examination found a huge pelvic mass with left deep vein thrombosis consequent by pressure effect. Chest and
complete abdominal computed tomography revealed an enlarged, fibroid uterus with pressure effect at left common iliac vein.
A total abdominal hysterectomy and bilateral adnexectomy were performed. Intra-operative finding was scattered hyperpigment
spots at surface of the uterus and its tumor. Histopathological report showed metastatic malignant melanoma involving
myometrium and uterine serosa. Diagnosis of stage IV malignant melanoma (uterine metastasis) was achieved. The patient
was counseled about her diagnosis, stage, prognosis and further treatment.
Conclusion : Uterine metastatic malignant melanoma was a rare condition. This report represents the first case of a
cutaneous malignant melanoma involving a uterine leiomyoma in Thailand.
Keywords : Malignant Melanoma, Uterine Metastasis
