New PFO Device for Closure of Patent Foramen Ovale in Patients Who had a History of Cryptogenic Stroke; a Report of 14 Cases
Suphot Srimahachota MD*, Nakarin Sansanayudh MD**, Vorarit Lertsuwunseri MD*, Jiranut Cholteesupachai MD*, Pornthep Lertsapcharoen MD***
Affiliation : * Cardiac Center and Division of Cardiovascular Disease, Department of Medicine, King Chulalongkorn Memorial Hospital and Chulalongkorn University, Bangkok, Thailand ** Cardiology Unit, Department of Medicine Phramongkutklao Hospital, Bangkok, Thailand *** Division of Pediatrics Cardiology, Department of Pediatrics, King Chulalongkorn Memorial Hospital and Chulalongkorn University, Bangkok, Thailand
Objective : The Cocoon PFO Occluder is a device for percutaneous closure of inter-atrial communications. Its self-centering
characteristics make it attractive for closure of patent foramen ovales (PFOs) with or without atrial septal aneurysms. The
goal of this study is to report the immediate and follow-up results of the first 14 patients in implanted with the Cocoon PFO
Occluder.
Material and Method: This is a retrospective report of immediate and short-term clinical and echocardiographic outcome
of patients who underwent transcatheter closure of PFO because of paradoxical embolism. Procedural success was defined
as successful deployment of the device and effective occlusion (no, or trivial, shunt after device placement). All patients had a
transesophageal echocardiography (TEE) with saline contrast injection at baseline and clinical follow-up at 6 months.
Results : Between September 2012 and March 2014, 14 patients had successfully undergone transcatheter closure of PFO
using Cocoon® device. During follow-up none of the patients had a recurrence of stroke after device closure. No residual
shunt was observed in any patients at follow-up.
Conclusion : Transcatheter closure of PFO with the Cocoon PFO device is safe and effective and can be used for preventing
recurrent strokes in patients who present with cryptogenic stroke and PFO.
Keywords : Patent foramen ovale, Closure device, Cryptogenic stroke
