Survival Rate of Recurrent Cervical Carcinoma
Kanate Thanagumtorn MD*
Affiliation : *Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand
Objective : To determine the survival rate of recurrent cervical carcinoma and clinical variables influencing survival.
Material and Method: Eighty eligible patients with recurrent cervical carcinoma were identified from the tumor registry
record of gynecologic oncology division, Rajavithi Hospital between January 2004-December 2010. The pathological and
clinical data were retrospective reviewed. Numerous clinical variables were analyzed including age, histopathology, primary
staging, site of recurrence, complete treatment time to recurrence and initial treatment after recurrence.
Results : Among the 80 patients, mean age of the patients were 48.11 years (SD = 9.62). Median time from complete primary
treatment to recurrence was 11.7 months. Fifty four cases (67.5%) were squamous cell carcinoma and the others were non-
squamous cell carcinoma. Seventy two cases (90.1%) were previously treated with radiation therapy. Sixty six cases (82.5%)
had only pelvic recurrence without distant disease. Median follow-up period of the present study was 14.2 months. Two-year
survival rate of the group was 33.7%, median survival was 15.4 months. Two years survival rate of the patients received
surgery, radiation, chemotherapy and supportive only as initial treatment after recurrence were 43.6%, 53.3%, 18.1% and
25.0%, respectively. Whereas median survival of the patients received surgery, radiation, chemotherapy and supportive only
as initial treatment after recurrence were 20.7, 24.5, 11.4 and 10.8 months respectively. Site of recurrent and type of initial
treatment modality after recurrence had statistic significance in multivariable analysis (p = 0.001 and p = 0.026, respectively).
Conclusion : Survival rate of recurrent cervical carcinoma was poor. Surgery and radiation as initial treatment modality
after recurrence may have survival benefit in well selected patients.
Keywords : Recurrent cervical cancer, Survival rate
