Invasive Vibrio cholerae Non-O1 Non-O139 Infection in a Thalassemic Child
Warunee Punpanich MD, PhD*, Pugpen Sirikutt MD*, Naris Waranawat MD*
Affiliation : *Department of Pediatrics, Queen Sirikit National Institute of Child Health, College of Medicine, Rangsit University, Bangkok, Thailand
Invasive, extra-intestinal infection with Vibrio cholerae non-O1, non-O139 is rare especially among children. Herein the authors report a 12- year-old girl with underlying β-thalassemia status post-splenectomy presenting with V. cholerae non-O1, non-O139 gastroenteritis with concomitant septicemia. The pathogen was identified from stool and blood culture and the patient recovered uneventfully after antimicrobial and supportive therapy. A review and comparison of clinical manifestations and outcomes with the previous four cases of invasive V. cholerae non-O1, non-O139 in post- splenectomy thalassemic pediatric patients is reported.
Keywords : Vibrio cholera non-O1, non-O139, Gastroenteritis, Septicemia, Thalassemia, Children
