The Association between Bone Mineral Density and Complete Blood Count in Postmenopausal Women: A Cross-Sectional Study

Jirapong Leeyaphan MD¹, Yuthasak Peerakul MD¹, Chayanan Sittibusaya MD¹

Affiliation : ¹ Bamrasnaradura Infectious Diseases Institute, Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand

Objective : To demonstrate the relationship between anemia and complete blood count (CBC) parameters with bone mineral density (BMD) in postmenopausal women.

Materials and Methods : A cross-sectional chart-review study was conducted between November 2017 and June 2019. Three hundred twenty-four postmenopausal women aged 50 years or older who had BMD and CBC results were included in the present study.
Results : The prevalence of osteopenia and osteoporosis diagnosed by T-score were 53.1% and 32.7%, respectively. Simple and multiple linear regression analyses showed that no association between CBC parameter with BMD except basophil count, which was negatively associated with BMD (p=0.011). There was no correlation between anemia and BMD status (p=0.168).
Conclusion : CBC parameters such as hemoglobin or white blood cell count were not statistically correlated with BMD. This is the first study demonstrating that basophil count may be an associated factor for deceased BMD.

Received 24 August 2020 | Revised 17 November 2020 | Accepted 3 December 2020
doi.org/10.35755/jmedassocthai.2021.03.11848

Keywords : Keywords : Postmenopausal women, Bone mineral density, Complete blood count, Basophil

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