Which Treatment Modality is the Best for Advanced Buccal Mucosa Cancer?
Jenwitheesuk K, MD1, Surakunprapha P, MD1, Chowchuen B, MD, MBA1, Winaikosol K, MD1, Punyavong P, MD1, Sawanyawisuth K, MD2
Affiliation : 1 Division of Plastic & Reconstructive Surgery Unit, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Objective : The present study aimed to evaluate the efficacy of various treatment modalities for advanced buccal mucosa cancer.
Materials and Methods: This was a retrospective study conducted at the Division of Plastic and Reconstructive Surgery in the
Department of Surgery at Khon Kaen University’s Faculty of Medicine (Khon Kaen, Thailand). The study period was between 2006
and 2010. The inclusion criterion was diagnosis with buccal mucosa cancer at any stage.
Results : There were 101 patients with buccal mucosa cancer who met the study criteria. A majority of the patients were elderly,
with 40.6% being 70 to 79 years old and 35.64% being 60 to 69 years old. Eighty-one (80.2%) patients were female and 20 were male.
The overall median survival time for all stages was 12.5 months, with a range of 0.6 to 146.6 months. The survival outcomes of
combination therapy consisting of surgical resection and chemoradiation did not differ from those of surgery plus radiotherapy.
Conclusion : A combination therapy for advanced buccal mucosa cancer consisting of surgical resection and chemoradiation did
not differ from surgery plus radiotherapy in terms of survival.
Keywords : Survival rate, Oral cancer, Surgical resection, Radiotherapy, Chemoradiation, Buccal carcinoma
