Complications in Acute Ischemic Stroke Patients during Endovascularization Therapy: A Retrospective Study
Phuriphong Songarj MD1, Chutida Sungworawongpana MD1, Natchanan Uhtsapun MD1
Affiliation : 1 Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
Objective : The present study aimed to determine the preferential technique of anesthesia, and compare the peri-procedure or
treatment complications in acute ischemic stroke patients who received endovascular recanalization therapy.
Materials and Methods : A retrospective descriptive cross-sectional study, data were collected from a list of patients who
received endovascular recanalization therapy from January 2014 to December 2015. Data from all patients were retrieved
from a database of the department of anesthesiology, Faculty of Medicine Siriraj Hospital. Baseline data were collected
including age, sex, comorbidities, current medication, Glasgow Coma Scale [GCS] and stroke severity. Intra-procedural data
and post-procedural complications were collected.
Results : Ninety-one patients were enrolled to the present study, 86% received general anesthesia [GA]. All baseline patients’
characteristics were similar in both groups, except patients in local anesthesia [LA] group receiving anti-coagulants much
more than GA group (p = 0.004). The overall procedure time and time record in stroke fast tract protocol were similar in both
groups. In GA group found peri-procedural hypotension significantly greater than LA group (p<0.001). Hypertension and
re-stroke were found in LA group, significantly greater than GA group (p = 0.034, p = 0.048).
Conclusion : GA was more preferable technique than LA in patients undergoing endovascular recanalization therapy. LA
provided less hypotension than GA during procedure. The patients receiving LA suffered from hypertension and re-stroke
more than GA in post-procedural period. Both GA and LA did not show greater improvement in neurological status at 24
hours after treatment.
Keywords : Complication, Acute ischemic stroke, Endovascular, recanalization, treatment, Retrospective
