Intravascular B-Cell Lymphoma Presenting Solely with Generalized Telangiectasia on Normal-Appearing Skin: A Case Report
Charoen Choonhakarn MD1, Narachai Julanon MD1, Suteeraporn Chaowattanapanit MD1, Nattiya Teawtrakul MD2
Affiliation : 1 Division of Dermatology, Department of Medicine, Srinagarind Hospital Medical School, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 Division of Hematology, Department of Medicine, Srinagarind Hospital Medical School, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Intravascular lymphoma is a rare type of lymphoma with a poor prognosis. Patients most often present with cutaneous or central nervous system findings. Its early diagnosis appears very important since it may be curable with appropriate chemotherapy regimens. A 61-year-old man who initially presented with diffuse arborizing telangiectasia on normal-appearing skin and limb edema is described. Skin biopsy and immunohistochemical studies confirmed intravascular B-cell lymphoma. After eight courses of treatment with combination chemotherapy (rituximab, cyclophosphamide, adriamycin, vincristine, and prednisolone) the outcome was complete remission after an 18-month follow-up.
Keywords : Intravascular lymphoma, B-cell, Telangiectasia
