Arinrada Ladla RN1, Suprawita Saensak PhD2, Pramote Tongkrajai PhD3, Sompong Srisaenpang MD, PhD4, Kittisak Sawanyawisuth MD, PhD5
Affiliation : 1 PhD Student in Health Science, Faculty of Medicine, Mahasarakam University, Mahasarakam, Thailand 2 Gradutaed Studies Division, Faculty of Medicine, Mahasarakam University, Mahasarakam, Thailand 3 Gradutaed Studies Division, Faculty of Medicine, Mahasarakam University, Mahasarakam, Thailand 4 Department of Community Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 5 Sleep Apnea Research Group, Research Center in Back, Neck and Other Joint Pain and Human Performance, Research and Training Center for Enhancing Quality of Life of Working Age People, Khon Kaen University, Khon Kaen, Thailand
Cardiovascular diseases are the main cause of death and disability. Metabolic syndrome is a group of several conditions that has been shown to be a major cardiovascular risk factor. A meta-analysis conducted in 2009 found that metabolic syndrome is associated with cardiovascular diseases for 2.35 times. However, the study included various study populations. This study aimed to evaluate and update the cardiovascular risks of metabolic syndrome in hospital setting. Literature searching was performed under the standard of the Cochrane Handbook on nine databases. There were seven studies conducted on risk of cardiovascular diseases by metabolic syndrome. There were 13,216 patients with 3,069 patients (23.22%) diagnosed as metabolic syndrome. Overall relative risk for cardiovascular diseases by presence of metabolic syndrome was 1.88 (1.61, 2.19). Subgroup analysis by study sites and sex were also performed. The relative risks of cardiovascular diseases by metabolic syndrome for Asia, non-Asia, male, and female were 2.19, 1.79, 1.66, and 2.28. In conclusion, patients with metabolic syndrome in hospital setting are at risk for major cardiovascular diseases regardless of continents or sex.
Keywords : Relative risk, Sex, Ethnicity
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