Survival Rate and Effect of Clinicopathological Characteristics on Survival of Rectal Cancer in Thailand
Phaiboon Pensuwan MD1, Narongchai Sangsa MD2, Chitkhet Tomuen MD3, Chatchawan Wachirametharuch MD1, Kriengkrai Kovitangkoon MD4, Nuntiput Putthanachote DrPH5, Pongdech Sarakran PhD6
Affiliation : 1 Department of Surgery, Roi Et Hospital, Roi Et, Thailand 2 Department of Medicine, Roi Et Hospital, Roi Et, Thailand 3 Cancer Registry Unit, Roi Et Hospital, Roi Et, Thailand 4 Department of Pediatrics, Roi Et Hospital, Roi Et, Thailand 5 Department of Clinical Microbiology, Roi Et Hospital, Roi Et, Thailand 6 Department of Epidemiology and Biostatistics, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
Objective : To investigate the survival rate and effect of clinicopathological characteristics on survival of rectal cancer in a Thai
population.
Materials and Methods : A retrospective cohort study was performed. All data were collected from medical records of
patients with rectal cancer at Roi Et Hospital during January 1, 2010 to December 31, 2014. All cases were followed-up until
death or to the end of the study (March 31, 2016).
Results : A total of 145 patients had rectal cancer and most of them were men (56.55%), with a mean age of 61.86+12.95
years. The total follow-up time was 6,284 person-months. The median survival time was 55.7 months. Six-month and 1-,
2-, 3- and 5-year survival rates were 97.92%, 92.36%, 86.73%, 77.44%, and 36.67%, respectively. The factors affecting
survival included cancer stage III (adjusted HR = 1.45; 95% CI: 1.16 to 2.43), cancer stage IV (adjusted HR = 3.04; 95% CI:
1.25 to 7.41), radiotherapy (adjusted HR = 0.46; 95% CI: 0.23 to 0.95), and chemotherapy (adjusted HR = 0.67; 95% CI:
0.17 to 0.87).
Conclusion : Rectal cancer stage III and IV affect the hazard of death. Patients who receive radiotherapy and chemotherapy
have a lower risk of death and better survival rate than those who do not.
Keywords : Rectal cancer; Survival rate, Chemotherapy
