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The Accuracy of Intraoperative Frozen Sections in Epithelial Ovarian Tumor

Korrakot Soitong MD¹, Tharintorn Chansoon MD¹, Chompunoot Kongsawatvorakul MD²

Affiliation : ¹ Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand ² Department of Obstetrics and Gynecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand


Objective : To evaluate the accuracy of the intraoperative frozen section in the diagnosis of epithelial ovarian tumor.
Materials and Methods : An observational study of epithelial ovarian tumor reports from patients that underwent surgery with intraoperative consultation at Ramathibodi Hospital, Thailand between 2013 and 2017 was done. The frozen section diagnoses were compared with the final surgical diagnoses and the overall accuracy, sensitivity, specificity, positive predictive values (PPV), negative predictive values (NPV) were studied.
Results : One hundred sixteen ovarian specimen reports were reviewed, comprised of 74 (63.8%) benign, 21 (18.1%) borderline, and 21 (18.1%) malignant neoplasms. Nine cases (7.7%) were discordant diagnoses. The overall accuracy was 92.2%. The sensitivity and specificity for benign, borderline, and malignant neoplasms were 100%, 80.9%, and 76.2%, and 88.1%, 95.8%, and 100%, respectively. The PPV and NPV for benign, borderline, and malignant neoplasms were 93.7%, 80.9%, and 100%, and 100%, 95.8%, and 95.0%, respectively.
Conclusion : The intraoperative frozen section has high accuracy in the diagnosis of ovarian epithelial neoplasm. The results can be used in guidance on the extent and type of surgical management.

Received 15 May 2020 | Revised 25 September 2020 | Accepted 29 September 2020
doi.org/10.35755/jmedassocthai.2021.02.11473

Keywords : Frozen section, Accuracy, Epithelial ovarian tumor


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