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Conservative Treatment for Endometrial Cancer: Survey of Practice among Thai Gynecologic Oncologists

Chandeying N, MD1, Chanpanitkitchot S, MD2, Kantathavorn N, MD3,4, Tangjitgamol S, MD1, Thai Gynecologic Cancer Society (TGCS)5

Affiliation : 1 Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand 2 Department of Obstetrics and Gynecology, Rajavithi Hospital College of Medicine, Rangsit University, Bangkok, Thailand 3 Faculty of Medicine and Public Health, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand 4 Chulabhorn Hospital, HRH Princess Chulabhorn College of Medical Science, Chulabhorn Royal Academy, Bangkok, Thailand 5 Office of the Thai Gynecologic Cancer Society, Bangkok, Thailand

Objective : To evaluate the practice of Thai gynecologic oncologists on conservative treatment for endometrial cancer patients and influencing factors. Materials and Methods: This study was a part of the national survey by the Thai Gynecologic Cancer Society (TGCS) on the management of gynecologic cancer. All Thai Gynecologic Oncologists who had been in practice for at least 1 year were invited to respond to the web-based questionnaire which was active from August to October, 2019. Data involving the practice of conservative treatment for endometrial cancer patients were abstracted and analyzed.
Results : of 170 respondents, 85.3% considered conservative treatment options if the patient needed childbearing. Among the respondents who considered conservative treatment, 84.1% considered one or more clinic-pathological features for conservative treatment. The two most frequent features of which included an absence of myometrial invasion (82.8%) and low-grade tumor (78.6%). The respondents working in training hospitals considered tumors without myometrial invasion more frequently than those in service-only hospitals (89.6% vs. 75.0%; p = 0.020. No significant differences of other clinic-pathological features were noted across the different hospital settings or duration of practice.
Conclusion : Most of Thai gynecologic oncologists considered conservative treatment option if the patient needed childbearing. The most frequently considered features were an absence of myometrial invasion and low-grade tumor.

Keywords : Survey, Practice, Endometrial cancer, Conservative treatment


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