Roles of Self-Sampling for Human Papillomavirus in Developing Countries
Chaichan S1,2, Sawanyawisuth K, MD3, Limpawattana P, MD3, Watcharenwong P, MD3, Chindaprasirt J, MD3,4, Chotmongkol V, MD3, Kongbunkiat K, MD2,3, Chattakul P, MD3, Sittichanbuncha Y, MD5, Khamsai S, MD3
Affiliation : 1 Medical student, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 North-Eastern Stroke Research Group, Khon Kaen University, Khon Kaen, Thailand 3 Department of Medicine, Faculty of Medicine, and Sleep Apnea Research Group, Khon Kaen University, Khon Kaen, Thailand 4 Cancer Research Group, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 5 Department of Emergency Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Objective : To evaluate whether or not self-sampling for human papilloma virus (HPV) infection in developing countries is acceptable
and sensitive.
Materials and Methods : A sub-group analysis of a previous review published by Madzima et al. The primary outcome of the present
study was either acceptability or sensitivity of HPV self-sampling compared with the Pap test.
Results : There were 43 relevant studies, four of which were conducted in developing countries. Three studies assessed the
acceptability of the self-sampling method and one evaluated its sensitivity. There were 21,965 eligible participants. The acceptability
rate of self-sampling was 82 to 98%, and its sensitivity was 4.2 times better than cytology in cases of invasive cervical cancer.
Conclusion : Self-sampling for HPV is highly acceptable and may be more sensitive than cervical cytology in developing countries.
Keywords : Acceptability, Human papilloma virus, Self-sampling test, Sensitivity
