Clinical Characteristics and Complications of Obstructive Sleep Apnea in Srinagarind Hospital
Sanlung T, MD1,2, Sawanyawisuth K, MD1, Silaruks S, MD1, Chattakul P, MD1, Limpawattana P, MD1, Chindaprasirt J, MD1, Chotmongkol V, MD1, Senthong V, MD1, Kongbunkiat K, MD1, Timinkul A, PhD3, Phitsanuwong C, MD4, Sawunyavisuth B, DBA5, Khamsai S, MD1,6
Affiliation : 1 Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 2 North-Eastern Stroke Research Group, Khon Kaen University, Khon Kaen, Thailand 3 Bachelor of Thai Traditional Medicine Program, Udon Thani Rajabhat University, Udon Thani, Thailand 4 Pritzker School of Medicine, University of Chicago, Chicago, Illinois, USA 5 Department of Marketing, Faculty of Business Administration and Accountancy, Khon Kaen University, Khon Kaen, Thailand 6 Sleep Apnea Research Group, Khon Kaen University, Khon Kaen, Thailand
Objective : To study clinical presentations and complications of OSA in Thai patients.
Materials and Methods : The present study was a retrospective, descriptive study conducted at OSA clinic, Srinagarind Hospital,
Khon Kaen University, Khon Kaen, Thailand. The inclusion criteria were adult patients diagnosed as OSA. The diagnosis of OSA was
made by evidence of apnea-hypopnea index of 5 times/hour or more by either in-laboratory or portable home sleep test. Clinical
presentations and complications of OSA were studied by chart review.
Results : There were 130 patients met the study criteria. The median age and body mass index of all patients were 50 years and 29.5
kg/m2. The male: female ratio was 1.1: 1.0. Snoring was the most common symptom (63.8%) followed by excessive daytime sleepiness
(41.5%). The median AHI and lowest oxygen saturation were 19 times/hour and 83.5%. The top three complications were
hypertension (80.8%), left ventricular hypertrophy (38.3%), and gastroesophageal reflux disease or GERD (36.9%).
Conclusion : Clinical presentations of OSA in Thai patients may not be obvious as previously reported. Hypertension, left ventricular
hypertrophy, and GERD may be suggestive complications of OSA.
Keywords : Hypertension, Left ventricular hypertrophy, Gastroesophageal reflux disease
